Scoperti i geni che decidono il successo dell’immunoterapia contro i tumori

Un test genetico potrà stabilire la risposta dei malati di tumore all’immunoterapia, aprendo così la strada a migliori possibilità di cura, più personalizzate. E’ infatti da alcuni geni che dipende l’efficacia o meno di questa terapia. Il risultato è descritto sulla rivista Immunity da Davide Bedognetti, dell’Università di Genova e Direttore del Cancer Program del …

Cytokine Storms in Cancer and COVID-19

Main Text SARS-CoV-2 is the fifth betacoronavirus to infect humans and has led to the current COVID-19 pandemic. Over 30 million people have been infected worldwide, and mortality continues to rise to over 1 million. Cancer remains a worldwide disease, causing an estimated of 9.8 million deaths per year. “Cytokine storm” or “cytokine release syndrome” …

Cancer stem cell targeted therapies

Ugo Testa, Elvira Pelosi, Germana Castelli Abstract In normal dividing tissues, cell homeostasis is maintained by rare cellular elements, the stem cells, that have the unique property of self-renewal and differentiation to generate a population of functionally mature tissue elements. Recent studies carried out in the last three decades support the existence of stem cells …